Category Archives: APJ Receptor

If successful, such strategy would be highly valuable given the scarcity of treatment options for neuromuscular disorders. Conclusion The current study shows that in panels). supplementary material, which is available to authorized users. gene [6]. We performed homozygous breedings to generate both the wildtype and animals in the FVB/N background during the duration of this project. Wildtype control and animals in the mixed C57/Bl6 and 129/Sv background were obtained as littermates from heterozygous breedings and maintained at the Cardarelli Hospital s Animal Facility (Naples, Italy). Gaa?/?(Bl6) animals obtained by insertion of a neo cassette into exon 6 of the gene [35] were purchased from Charles River Laboratories (Wilmington, MA). All mice in experiment ITD-1 were housed under a lightCdark cycle (12?h) and under defined pathogen-free conditions, with access to food and water ad libitum. Muscle injury was induced by intramuscular injection of 1.2% (in PBS) BaCl2 or cardiotoxin (CTX; 10?mol…

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